Can sleeping pills be taken long-term? How long does it take for them to take effect? ​​Are there any side effects?

This article focuses on the three most common questions about the use of sleeping pills:

Can it be taken long term? How long does it take for the effect to take effect? ​​Are there any side effects? Combining the clinical research and pharmacological characteristics of new sleeping aids such as suvorexant, lebrexant, and dalisant, this book provides readers with a clear and scientific reference for medication.

 

1. Can you take sleeping pills for a long time? It depends on which one you take.

Many people stay away from sleeping pills for fear of addiction , and even when faced with severe insomnia, they still dare not try them.

But in fact, whether it can be used for a long time depends on the type and mechanism of action of the sleeping pill .

📌 Traditional sleep aids (such as benzodiazepines, non-benzodiazepines):

       Such as diazepam, alprazolam, zopiclone, etc.

       Directly enhance the activity of the GABA system and forcibly inhibit nerve excitation .

       It is easy to cause dependence and tolerance , and long-term use requires continuous increase in dosage. It is not recommended to use it for more than 4 weeks ( Lader, 2011 ).

📌 New generation of sleep aids (orexin receptor antagonists ORAs ):

       Such as Suvoreshen, Leboreson, and Dalireson .

       By inhibiting the brain's " arousal system " , it helps people fall asleep naturally without disturbing the balance of neurotransmitters.

       It is non-addictive and non-drug-resistant, and has been clinically proven to be safe for use for more than 6 months ( Ueno et al., 2022 ; Sun et al., 2021 ).

Conclusion: Traditional sleeping pills are not recommended for long-term use, while new sleeping pills can manage sleep problems in the long term and will not rebound after stopping the medication.

 

2. How long does it take for sleeping pills to take effect? ​​It may be different for everyone

📌 The time it takes to take effect varies depending on the drug:

Drug Name

Average onset time

Main Function

Suitable for

Leibersson

About 30 minutes

Faster sleep

Difficulty falling asleep, anxiety-type insomniacs

Suvorex

30-60 minutes

Reduce nighttime awakenings

Sleep maintenance disorder

Dale Raisin

About 60 minutes

Improve the proportion of deep sleep

Those who have light sleep and feel tired when waking up in the morning

📌 Note:

       The first use of the medication may be slightly delayed due to emotional factors such as anxiety , and frequent changes are not recommended.

       The onset time is also closely related to the sleeping environment, diet, and daily routine . After taking the medicine, you should avoid light stimulation and the use of electronic devices.

       If the medication is still ineffective after taking it, you should consult a doctor to adjust the dosage or change the medication. It is not recommended to increase the dosage on your own.

 

3. Will there be side effects? The new generation of drugs is milder and safer

Compared with traditional drugs, new sleeping aids have significant improvements in side effects.

📌 Common side effects (rarely occur and are mostly mild):

drug

Possible side effects

Remark

Suvorex

Mild morning sleepiness, occasional increased dream clarity

Generally, it will gradually improve with the use of time

Leibersson

Drowsiness, dizziness

Usually a short-term adaptation reaction

Dale Raisin

Dry mouth, occasional headache

The incidence rate is lower than traditional sleeping pills

📌 Compared with traditional sleeping pills:

       It does not affect cognition or memory and does not increase the risk of falling.

       No rebound insomnia or withdrawal reaction occurs after discontinuation of the drug ( Sun et al., 2021 ).

       It is well tolerated in the elderly population ( Dauvilliers et al., 2022 ).

 

4. Use with caution or consult a doctor first in the following situations:

Although new sleeping pills are relatively safe, the following groups are still recommended to be evaluated before taking the medicine:

       Pregnant and lactating women

       Those with severe liver and kidney dysfunction

       Long-term use of other central nervous system drugs

       People with a history of sleep apnea or nocturnal behavior disorders

📌 Medication recommendations:

       Take it 30 minutes before bedtime and ensure at least 7 hours of sleep .

       Start with the recommended dose for the first time and do not increase the dose on your own or use with alcohol .

 

5. Conclusion: It is more important to use sleeping pills scientifically and establish a good sleep rhythm.

Sleeping aids are not something you become more and more dependent on the more you take them. The key lies in whether you choose a drug that is suitable for you and has a mild mechanism .Newer medications like suvorexant, lebrexant, and darilexant help restore your natural sleep by modulating your wakefulness signals without disrupting your sleep architecture .

At the same time, the following habits should also be adopted:

       Fixed work and rest schedule, limited nap time

       Stay away from electronic screens and light sources before going to bed

       Limit caffeine and alcohol intake

       Maintain moderate exercise

📌 Taking medicine is not the end, but a step to help you get back to a healthy sleep rhythm . If you use it properly under the guidance of a doctor, you can definitely achieve the following: sleep well and take medicine with peace of mind.

 

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