"I took melatonin but it didn't work." What you may need is not hypnosis, but regulation of wakefulness!
1. Is melatonin really effective for all insomnia?
Many insomnia patients often choose melatonin, which " seems natural and harmless " , as a sleep aid before starting medication. But in reality, we often hear such feedback:
• " After taking melatonin, I still have to toss and turn for an hour or two before I can fall asleep. "
• “ There are no side effects, but it’s not very useful either. ”
• " I could fall asleep, but woke up again in the middle of the night. "
📌 In fact, the sleep-inducing effect of melatonin is subject to certain conditions and is not applicable to all types of insomnia .
2. The principle of melatonin: helping you " time " but not " shut down "
Melatonin is a hormone secreted by the pineal gland in the brain. Its main function is to transmit the signal that " it's dark, time to go to bed " . It plays the role of " starting " the sleep program in the natural sleep rhythm.
✅ Its effective premise is:
• Sleep rhythm disturbances (eg, jet lag, shift work, circadian rhythm disorder)
• Insufficient melatonin secretion (more common in the elderly)
❌ But it does not solve the following problems:
• The brain is still in an excited state
• Awakening system is too active
• Sleep disorders caused by anxiety and nervous sensitivity
In other words: melatonin is like " notifying you that it's time to turn off the lights " , but the " lights " in your brain may not actually turn off.
3. The key to not being able to sleep may be that the " awakening system is too strong "
Scientific research has found that there is a powerful " wakefulness maintenance system " in the brain - the Orexin System .
When you:
• My mind is always on something and I can’t put my phone down
• Feeling anxious or nervous before going to bed
• Waking up in the middle of the night and becoming rapidly awake and having difficulty falling asleep again
You may not be " missing hypnotic signals " , but your wakefulness system may be working continuously, overriding the effect of melatonin .
4. A new generation of sleeping pills that regulate wakefulness rather than simply induce hypnosis
This is where the new generation of sleep aids (such as suvorexant, lebrexant, and darilexant) come in:
|
Types of medication |
Mechanism of action |
Applicable issues |
|
Melatonin |
Start the sleep routine |
Biological clock disorder, mild circadian rhythm disorder |
|
New sleeping pills ( ORAs ) |
Blocks orexin receptors, reducing arousal signals |
Brain hyperactivity, night wakings, anxiety-related insomnia |
These drugs regulate OX1R/OX2R receptors to balance the signal ratio of " time to be awake " and " time to fall asleep " from the source , allowing the brain to truly relax and enter a natural sleep state.
5. Three drug recommendations and corresponding populations
|
drug |
Features |
Suitable for |
|
Suvorex |
Strong sleep maintenance ability, reducing nighttime awakenings |
Those who wake up in the middle of the night and cannot fall back asleep |
|
Leibersson |
Fast-acting, helps you fall asleep |
Difficulty falling asleep, anxious insomniacs |
|
Dale Raisin |
Improve deep sleep quality and feel refreshed during the day |
Those who have shallow sleep, frequent dreams, and feel tired when waking up in the morning |
📌 Clinical studies have shown that ORAs have no tolerance after 6-12 months of use, and sleep rhythm can still be maintained after discontinuation of the drug ( Sun et al., 2021 ; Ueno et al., 2022 ).
6. Conclusion: The reason why you can’t fall asleep is not because you lack the “ sleep signal ” , but because you wake up too thoroughly
If melatonin doesn't work for you, it's not because your body is " out of control " but because your brain is too awake. If you want to really get into a good sleep state, what you need to adjust is not the " sleep command " but the " wake-up system " .
📌 Instead of trying melatonin again and again, it is better to learn about the new generation of sleeping aids such as Suvorexant, Lebrexant and Darilexant, which are scientific, gentle and long-term available. They may really be the right medicine for your insomnia.
🛒Leborexant 2.5mg 100 tablets / box
🛒Lebrexan 5mg 100 tablets / box
🛒Leborexant 10mg 100 tablets / box
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