2024 Latest News of Tesiparatide: Approved for Weight Loss Indications! A New Choice for Scientific Weight Loss
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With the official approval of Tirzepatide for weight loss in 2024 , the global weight loss medical field has ushered in a revolutionary breakthrough. This news is of great significance to the vast number of people suffering from obesity.
1. Tesiparatide is approved for weight loss: a major medical breakthrough in 2024
In early 2024 , the U.S. Food and Drug Administration (FDA) officially approved tesiparatide for chronic weight management, a decision based on the excellent results of multiple clinical trials. In the SURMOUNT series of studies, participants using the highest dose of tesiparatide achieved an astonishing average weight loss of 21.1% , far exceeding the effect of existing weight loss drugs.
It is particularly noteworthy that tesiparatide was initially marketed as a treatment for type 2 diabetes ( trade name Mounjaro) , but during clinical use, both doctors and patients observed significant weight loss effects, which prompted pharmaceutical companies to conduct clinical trials specifically for obesity and ultimately obtain approval for weight loss indications.
2. Dual mechanism: Why is tesiparatide so effective?
The key reason why tesiparatide has caused a sensation in the field of weight loss is its unique " dual mechanism of action " :
- GIP/GLP-1 dual receptor agonist : It acts on glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide -1 (GLP-1) receptors at the same time, which is the biggest difference between it and a single GLP-1 receptor agonist.
- Triple function :
- Significantly reduces appetite and calorie intake
- Delay gastric emptying and increase satiety
- Improve energy metabolism and promote fat decomposition
- Metabolic improvement : In addition to weight loss, it can also improve multiple metabolic indicators such as blood sugar, blood lipids and blood pressure, and has a comprehensive management effect on obesity-related complications.
3. Who is suitable for using tesiparatide?
According to FDA approval information, the suitable population for tesiparatide for weight loss includes:
- Adult obese patients : BMI ≥ 30kg/m²
- Overweight with complications : BMI ≥ 27 kg/m² and at least one weight-related disease ( such as high blood pressure, type 2 diabetes or high cholesterol )
- Weight plateau group : those who have lost some weight through diet and exercise but have entered the plateau period
Table: BMI classification table for tesiparatide
|
BMI categories |
Applicable |
Additional conditions |
|
<27kg/m² |
not applicable |
- |
|
27-29.9kg/m² |
Applicable |
Must have at least one weight-related disease |
|
≥30kg/m² |
Applicable |
No strings attached |
IV. Guidelines for the use of tesiparatide: Dosage and course of treatment
Tesiparatide is injected subcutaneously, usually once a week. Standard treatment options include:
- Dose escalation :
- Starting dose: 2.5 mg/ week for 4 weeks
- Maintenance dose: gradually increase to 5mg , 7.5mg , 10mg , 12.5mg or 15mg depending on tolerance
- Best course of treatment :
- Minimum recommended treatment course: 12 weeks to evaluate the effect
- Long-term maintenance: Most patients need to continue using to maintain weight loss
- Combined treatment : It is recommended to cooperate with medical nutrition guidance and moderate exercise for better results
5. Frequently Asked Questions
Q : How long can the weight loss effect of tesiparatide last?
A : Clinical trials have shown that continued use can maintain weight loss for more than 72 weeks. Some patients may experience weight rebound after stopping the medication, so it is recommended to change your lifestyle.
Q : What are the common side effects?
A : The most common side effects are gastrointestinal reactions ( nausea, diarrhea, constipation, etc. ) , which are mostly mild to moderate and improve over time. Severe side effects are rare, but include pancreatitis, gallbladder disease, etc.
Q : What are the advantages compared with other weight loss drugs?
A: Compared with a single GLP-1 agonist, tesiparatide has a more significant weight loss effect ( average weight loss of about 5-7% more body weight ) and more comprehensive metabolic improvements.
6. Why choose us?
l Genuine Tesiparatide (Worldwide Cold Storage Delivery)
l Hospital prescription
l Online doctor consultation
l Pharmacist medication guidance
Scientific weight loss, healthy accompaniment! Tesiparatide provides a new option for obesity treatment, but everyone's situation is different, so it is recommended to develop a personalized weight loss plan under professional medical guidance. We hope that this innovative drug can help more people achieve a healthy weight and embrace a better life.
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