Is there a cure for slow metabolism and obesity? -- GLP-1/GIP dual agonists bring new hope

1. The root cause of obesity: slow metabolism ≠ eating too much

📌 Many people think they are fat because they “ eat too much ” , but in fact:

•       A low basal metabolic rate (low BMR ) means that even if you don't consume much, your body will have difficulty burning fat efficiently.

•       Insulin resistance makes it easier for the body to store food as fat rather than energy.

•       The fat oxidation ability is poor , and the fat eaten is not easily metabolized and accumulates in the internal organs, abdomen, and lower limbs.

📌 Behind it is often accompanied by:

•       Prediabetes, fatty liver, irregular menstruation, polycystic ovary syndrome and other metabolic disorders

•       Characteristics of " hormonal obesity " such as slow satiety, difficulty regulating appetite, and large fluctuations in blood sugar

 

2. The mechanism of action of tirpotide: restarting the " metabolic engine "

Tipoline is a GLP-1 + GIP dual agonist. Compared with traditional GLP-1 drugs, it has GIP , a key role in " promoting metabolism " , making it more suitable for people with " slow metabolism and poor basic condition " .

Agonists	Main Function	Advantages of Telpotide
GLP-1	Suppress appetite, delay gastric emptying, and promote insulin secretion	Control calorie intake and improve satiety
GIP	Enhance insulin sensitivity and promote fat oxidation	Improve basal metabolism and improve insulin resistance

📌 This dual mechanism allows tipol to not only " reduce what you eat " but also " increase your metabolism " , accurately attacking the fundamental problem of obesity-prone physique from two dimensions.

 

3. Clinical data: The poorer the foundation, the more obvious the effect

🔍 SURMOUNT-1 clinical study data show:

•       The average weight loss of the subjects was 22.5%

•       People with BMI ≥ 35 and metabolic syndrome had greater weight loss

•       Visceral fat decreased by approximately 32%

•       Insulin sensitivity significantly improved, diabetes risk reduced

📌 This means that the more people with " poor metabolism " and " prone to obesity " have more significant improvements under the intervention of telportin

 

4. Profile of people who are suitable for using telopoietin

📌 Particularly suitable for:

•       People who have repeated weight rebound and have a history of " ineffective dieting "

•       Those with high fasting blood sugar and insulin resistance

•       Those with a family history of fatty liver, polycystic ovary syndrome, or diabetes

•       People who have no feeling of long-term exercise, weak strength foundation, and little muscle mass

📌 Medication recommendations:

•       Start with 2.5 mg/ week, gradually increase to 5 mg , 10 mg , 15 mg

•       Dietary recommendations: high protein + low refined carbohydrate structure

•       Can be combined with light exercise, such as walking, brisk walking, and simple resistance training to improve fat utilization

 

5. Conclusion: It’s not that you don’t work hard, but you should change your approach

📌 If dieting doesn’t work and you don’t feel any effect from exercise, it’s not necessarily because you are lazy, but rather that your body’s metabolic mechanism is “ locked ” .

📌 By activating the dual pathways of appetite regulation and fat metabolism , tipol can fundamentally " unlock " the metabolic disorders of obesity-prone physiques.

💡 It is not about willpower, but choosing the right mechanism. Tipoline may be the new solution to the " obesity-prone physique " .

 

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