Do you always gain weight back? - This drug may break the cycle of weight loss

" It takes a lot of effort to lose weight, but it only takes a week to gain weight. "

“ Every time I successfully diet, I come back faster than before. ”

" I tried exercise, intermittent fasting, meal replacements ... but my weight kept increasing. "

If these experiences are familiar to you, then you need to understand that weight rebound is not a matter of willpower, but the body's biological instinct to protect fat . If you really want to get rid of the vicious cycle of " weight loss - rebound - weight loss again " , you can't just rely on eating less and exercising more, but also scientific intervention from the metabolic and hormonal mechanisms .

This time, the doctor recommended the " plan to break the rebound fate " : GLP-1/GIP dual agonist telpotide .

 

1. Why is traditional weight loss always prone to rebound?

📌 The underlying reasons are:

•       Decreased basal metabolism : Dieting leads to muscle loss, and the body enters " energy saving mode " . Even if you resume eating normally, it is easier to store fat.

•       Increased insulin resistance : Repeated weight loss disrupts insulin levels, making it easier for fat to accumulate.

•       Appetite hormone rebound : Once the appetite hormones (such as leptin) that are suppressed during weight loss rebound, it is easy to overeat and gain weight rapidly.

✅ Conclusion: Traditional weight loss methods only control short-term calorie intake and fail to fundamentally improve metabolic status and hormone balance, so rebound is inevitable.

 

2. How does tirpotide break the weight loss rebound cycle?

Telpotide ingredients	Mechanism of action	Weight loss features
GLP-1 agonists	Suppress appetite and delay gastric emptying	Naturally reduce intake and reduce hunger
GIP agonists	Enhance fat oxidation and improve insulin sensitivity	Promote fat burning and increase basal metabolic rate

📌 The dual activation mechanism means:

•       Not only do you eat less, you can also burn more

•       Not only reduces fat, but also maintains muscle

•       Not only short-term weight loss, but also long-term stability

✅ By regulating biological hormones rather than relying on willpower, telopoietin helps users reshape their weight regulation mechanisms and significantly reduce the rate of weight loss rebound.

 

3. Clinical research: long-term weight loss and lasting maintenance

📌 SURMOUNT-1 study ( 72 weeks) data highlights:

•       Average weight loss 22.5%

•       More than 57% of subjects lost ≥20% of their body weight

•       The body weight is well maintained after drug withdrawal, which is much lower than the rebound amplitude of traditional GLP-1 monoagonists.

Comparison of rebound effects of telolipide vs. traditional weight loss drugs

Drug / method	Weight maintenance rate (half year after stopping medication)	Remark
Telportide	More than 70% maintained a weight loss of more than 10%	Metabolic regulation stability
Semaglutide	About 50%	Some rebound
Diet + exercise	30%-40%	Most rebound quickly

✅ Conclusion: Through mechanism regulation, tepoxetine can break the old path of short-term thinness and long-term fatness and truly enter the " stable thinness period " .

 

4. Who is suitable for using tebuconazole to fight rebound?

📌 Recommended for:

•       People with a history of repeated weight loss failures and significant rebound

•       BMI ≥30 , or BMI ≥27 with metabolic abnormalities (such as diabetes, fatty liver)

•       People who want to maintain long-term stable weight

•       People who want to reduce their dependence on dieting and extreme exercise

 

5. How to use tirpotide scientifically?

📌 Recommended use:

•       The starting dose is 2.5 mg/ week, gradually increasing to 5 mg , 7.5 mg , 10 mg , and 15 mg.

•       A high-protein, low-refined carbohydrate diet

•       Moderate exercise every week (such as brisk walking + resistance training) to help increase muscle mass

•       Monitor weight and metabolic indicators regularly and adjust strategies

📌 Note:

•       Not recommended for use by breastfeeding or pregnant women

•       Contraindicated in patients with a family history of medullary thyroid cancer

•       If gastrointestinal discomfort occurs in the early stage, it is recommended to slow down the pace of increasing the dosage 

Conclusion: Losing weight is not a battle of willpower, but a repair of mechanism

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