Vigovi vs. Tipovidone: Which weight loss injection is better for you?
In recent years, GLP-1 receptor agonists have become a popular choice for weight loss management , with Vigovi (semaglutide) and Telportide being the two most popular weight loss injections . Both drugs have been approved by the U.S. Food and Drug Administration ( FDA ) and can effectively reduce weight and improve metabolic health.
Although they both belong to the GLP-1 class of drugs, there are still significant differences in their mechanisms of action, weight loss effects, side effects, and applicable populations . So, which one is more suitable for you? This article will make an in-depth comparison from many aspects to help you find the weight loss plan that best suits your needs.
1. Comparison of action mechanisms
|
drug |
Mechanism of action |
Main Features |
|
Vigovi (semaglutide) |
GLP-1 receptor agonists |
Mainly reduce appetite, delay gastric emptying, and reduce calorie intake |
|
Telportide |
GLP-1 + GIP dual agonist |
Additional increase in GIP effect, promote fat decomposition, improve insulin sensitivity |
Core differences :
• Vigoviq aids weight loss primarily by reducing appetite and delaying gastric emptying , with less direct effects on fat metabolism.
• In addition to reducing appetite, tipol can also promote fat decomposition and increase insulin sensitivity through the action of GIP , so the weight loss effect is stronger.
2. Comparison of weight loss effects: Which one is more effective?
|
drug |
Clinical research data |
Average weight loss |
|
Vigovi ( STEP-1 study) |
After 68 weeks, the highest dose group (2.4 mg ) |
16.9% weight loss |
|
Telpotide ( SURMOUNT-1 study) |
After 72 weeks, the highest dose group (15 mg ) |
22.5% weight loss |
Key data analysis :
• The weight loss rate of tebuconazole was 5.6% higher than that of Vigovi , which is the strongest effect among all FDA -approved weight loss drugs.
• In the SURMOUNT-1 study, more than 57% of tebuconazole users lost more than 20% of their body weight , compared with 36% of Vigovik users.
• Tipollution not only reduces calorie intake, but also accelerates fat burning, making weight management more efficient.
3. Side effect comparison: Which one is easier to tolerate?
|
side effect |
Vigovi (semaglutide) |
Telportide |
|
nausea |
high |
Low |
|
Vomit |
high |
Low |
|
Diarrhea / constipation |
May occur |
May occur |
|
Hypoglycemia (non-diabetic people) |
Low |
Low |
|
Weight rebound after stopping medication |
May be faster |
Relatively slow |
in conclusion :
• Due to the GIP effect, tebuconazole has milder gastrointestinal side effects than Vigovi and is better tolerated by users .
• The rate of weight regain after discontinuation of Vigovi is faster, while the long-term maintenance effect of tepoxetine is more stable .
4. Comparison of applicable populations: Who is more suitable for which drug?
|
Target Group |
Vigovi (semaglutide) |
Telportide |
|
Want moderate weight loss ( 10-15% body weight loss) |
✅ Suitable |
❌ Telportide may cause weight loss too quickly |
|
Desire to achieve maximum weight loss ( >20% body weight loss) |
❌ May be insufficient |
✅ More suitable |
|
Gastrointestinal sensitivity, nausea and vomiting |
❌ May be difficult to tolerate |
✅ Mild side effects |
|
I have used Vigovi but the effect was not satisfactory. |
❌ The goal may still not be achieved |
✅ Stronger weight loss effect |
|
People with prediabetes and metabolic syndrome |
✅ Suitable |
✅ Better fit ( GIP action can improve insulin sensitivity) |
|
Unwilling to adjust eating habits |
✅ Suitable |
✅ Suitable |
in conclusion :
• If the goal is moderate weight loss ( 10-15% body weight loss), Vigovi is a good choice .
• If the goal is to achieve substantial weight loss ( >20% body weight loss) or if Vigoviq is ineffective, tebuconazole is a better choice .
• People with sensitive gastrointestinal tracts are more suitable for tebuconazole because it has milder side effects .
5. Price and accessibility comparison
|
drug |
Price (monthly fee) |
Accessibility |
|
Vigovi (semaglutide) |
USD 1300-1600 |
Supply is tight and out of stock in some areas |
|
Telportide |
USD 1000-1300 |
Relatively stable supply |
• The price of tebuconazole is relatively lower and its supply is better , making it more friendly to users with limited budgets.
• Due to high demand in Vigovi, supply is tight in some areas and you may need to wait in line .
6.Which weight loss injection is more suitable for you?
1. The situation of choosing Vigovi: ✔ The goal is to lose 10%-15% of your body weight, but extreme weight loss is not necessary. ✔ Habitual overeating, hoping to reduce appetite. ✔ The budget is sufficient and can accept a higher price.
2. Situations in which telopoietin is selected: ✔ More substantial weight loss ( >20% body weight loss) is required. ✔ Vigovi has been used but has not been effective, or the gastrointestinal side effects are too strong. ✔ I have prediabetes, insulin resistance, and want to improve my metabolic health at the same time. ✔ The budget is limited and I want a more cost-effective weight loss solution.
Conclusion: If you want to lose a lot of weight, maintain your weight for a long time, and reduce side effects, tebuconazole is a better choice. If you only want to lose a little weight, Vigovi can also meet your needs. The final choice should be based on personal health status and budget.
