Dieting failed, exercise failed to lose weight? How does Telpotide break through stubborn obesity?
Many people try dieting, exercise, fasting, ketogenic diet and other methods to lose weight, but eventually find that weight loss is limited or even rebounds . This is because obesity is not just a problem of " eating too much and moving too little " , but a complex metabolic imbalance .
Traditional weight loss methods rely on personal willpower , but when the body's hormone regulation system is abnormal, simply reducing calorie intake or increasing exercise may not be able to maintain weight for a long time . This is why many patients with stubborn obesity still find it difficult to lose weight even if they adhere to a healthy lifestyle.
As the first GLP-1/GIP dual agonist weight loss drug , telopoietin ( Mounjaro/Zepbound ) can regulate appetite and improve metabolism from a physiological level, breaking through the limitations of traditional methods . So, how can it help those who have failed dieting and exercise to successfully lose weight? This article will analyze the advantages of telopoietin in detail and compare the limitations of traditional weight loss methods.
1. Why are traditional weight loss methods difficult to be effective in the long term?
📌 1.1. Metabolic adaptation: the body resists weight loss
• Long-term dieting will reduce the basal metabolic rate , and the body will enter " energy-saving mode " , making it easier to gain weight with the same diet intake than before .
• Studies show that more than 80% of dieters will gain the weight back within 2 years .
📌 1.2. Hormone regulation imbalance: increased appetite and increased hunger
• A decrease in leptin levels causes the brain to mistakenly believe that the body is " hungry " and increases appetite.
• Increased ghrelin levels make it more difficult to control eating and more likely to overeat.
📌 1.3. Exercise has limited effect on body weight
• Studies have shown that weight loss through exercise alone is not as effective as diet adjustments because, although exercise can burn calories, it usually does not affect the body's hunger signals, making it easier to eat after exercise.
• An hour of jogging burns about 600 kcal, but these calories can be easily replenished with a high-calorie meal .
📌 1.4. Fat storage mechanism: Visceral fat is more difficult to consume
• Visceral fat has low metabolic activity and is difficult to completely eliminate through exercise and diet alone . Excessive visceral fat is closely related to insulin resistance and metabolic disorders.
💡 Conclusion : Traditional dieting and exercise may be effective in the short term, but due to the influence of metabolic adaptation, hormone regulation and fat storage mechanism, long-term weight loss is difficult and the risk of rebound is high.
2. How does tirpotide break through stubborn obesity?
Tipoleptide ( Mounjaro/Zepbound ) is the first GLP-1/GIP dual agonist that not only reduces appetite, but also accelerates fat decomposition and increases metabolic rate , completely changing the way obese patients manage their weight.
2.1. Telpotide vs. Traditional Weight Loss Methods: Core Differences
|
Way |
Main Function |
Long-term weight loss effects |
Risk of weight regain |
Target Group |
|
Diet |
Reduce calorie intake |
Effective initially, but long-term metabolism declines |
High, due to metabolic adaptation and hormonal changes |
Suitable for slightly overweight people |
|
sports |
Improve energy consumption |
Limited effect on body weight, but helps maintain weight loss |
Moderate, difficult to lose weight through exercise alone |
Suitable for health management |
|
Traditional weight loss medications (such as orlistat) |
Inhibit fat absorption |
Moderate effect ( 7-10% weight loss) |
High, weight gain after stopping medication |
Suitable for people with mild obesity |
|
GLP-1 monoagonist (semaglutide) |
Suppress appetite and delay gastric emptying |
Moderate ( 16-17% weight loss) |
Some people regain weight after stopping medication |
Suitable for people with obesity-related diseases |
|
GLP-1/GIP dual agonist (Telportide) |
Reduce appetite + promote fat decomposition + enhance insulin sensitivity |
The strongest effect ( 22.5% weight loss) |
Low, due to GIP effect to improve metabolism |
Suitable for all patients with stubborn obesity |
2.2. Unique advantages of tepote
- GLP-1 effect: Reduce appetite and calorie intake
• It acts on the hypothalamic appetite center of the brain, reduces hunger, and causes patients to naturally reduce the amount of food they eat .
• Delays gastric emptying , allowing food to stay in the stomach longer and reduce eating frequency.
- GIP function: promote fat burning and improve metabolism
• Traditional GLP-1 drugs (such as semaglutide) mainly rely on reducing appetite, while the GIP effect of tepote can accelerate fat oxidation , especially stubborn visceral fat .
• Studies have shown that tebuconazole can more effectively reduce abdominal fat accumulation while maintaining muscle mass, avoiding physical deterioration caused by simply losing weight.
- Improve insulin sensitivity and reduce abnormal glucose metabolism
• Many obese people have insulin resistance problems , and even if they control their diet, it is difficult for them to effectively lose weight.
• Tipollution can enhance insulin sensitivity, reduce fat storage, and improve energy metabolism , and is particularly effective for people with obesity and prediabetes.
💡 Conclusion : Compared with traditional weight loss methods, telopoietin can not only reduce calorie intake, but also promote fat decomposition, break the physiological barrier of obesity , and achieve long-term and effective weight management.
3. Conclusion: Who can tepoxetine help to break through the weight loss bottleneck?
📌 Target Group
✔ People who cannot lose weight effectively through long-term dieting and exercise
✔ People with visceral fat accumulation and abdominal obesity
✔ People with insulin resistance and prediabetes
✔ Those who want to lose 15%-20% or more of their body weight
📌 Advantages over traditional weight loss methods
✔ Will not reduce basal metabolism and reduce the risk of weight rebound
✔ Not only reduces appetite, but also accelerates fat burning and reduces visceral fat
✔ Improve insulin sensitivity and reduce the risk of diabetes
💡 Final conclusion : If you have tried dieting, exercise, and low-carb diets, but still cannot control your weight for a long time, telopoietin may be the best choice. Compared with traditional weight loss methods, it can start from hormone regulation, metabolic improvement, and appetite management to truly break through stubborn obesity.
🛒Mounjaro 2.5mg *2 sticks / box*2
Eli Lilly's official website introduces telportipeptide ( EN )
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