Does not affect daytime energy, no addiction! The safety of the new generation of sleeping pills revealed!
1. Why is the safety of sleeping pills so important?
The fast-paced life, long-term use of electronic devices, and high-pressure working environment in modern society are making insomnia an increasingly common health problem. More than 35% of adults worldwide have varying degrees of sleep disorders , of which 10% suffer from chronic insomnia ( Morin et al., 2020 ). Long-term insomnia not only leads to memory loss, weakened immunity, and emotional instability , but may also increase health risks such as hypertension, diabetes, cardiovascular disease, anxiety and depression ( Krystal et al., 2019 ).
However, many insomnia patients still have concerns about taking sleeping pills. They worry that they will become addicted to the pills, or even affect their daytime energy and work efficiency . In the past, traditional sleeping pills did have these problems, but with the advancement of medicine, ** new generation sleeping pills (such as Suvorexant, Lebrexant, Darilexant) ** are becoming the choice recommended by more and more doctors.
These new sleeping pills do not affect daytime wakefulness or make you more dependent on them , making them one of the safest long-term sleeping aids available. So, how safe are they?
2. Why do the side effects of traditional sleeping pills discourage people?
Benzodiazepines (such as diazepam, alprazolam) and non-benzodiazepines (such as zopiclone, zolpidem) are the most common sleep aids in the past few decades. They mainly enhance the inhibitory effect of GABA receptors, forcibly calm the nervous system , and let patients fall asleep quickly.
📌 The main problems with traditional sleeping pills :
1. It is easy to become addicted. Long-term use may lead to tolerance - the user needs to gradually increase the dosage to maintain the effect, and more severe insomnia may occur after stopping the drug ( Lader, 2011 ).
2️Affects deep sleep - Although it can help you fall asleep, it may inhibit rapid eye movement ( REM ) sleep and affect memory consolidation and brain repair ( Kuriyama & Endo, 2018 ).
3️ Feeling sleepy when waking up in the morning affects daytime wakefulness - Since some drugs have a long half-life, they may cause next-day drowsiness, decreased concentration, and even increase the risk of traffic accidents ( Billioti de Gage et al., 2014 ).
Research data shows that :
• Long-term use of benzodiazepines increases the risk of Alzheimer's disease by 50% ( Billioti de Gage et al., 2014 ).
• Patients taking non-benzodiazepines such as zopiclone have a 30% increased risk of morning sleepiness ( Kuriyama & Endo, 2018 ).
These side effects have prevented many patients from taking traditional sleeping pills for a long time, but the new generation of sleeping aids has completely changed this situation .
3. The core advantages of the new generation of sleeping pills: How to improve sleep while avoiding side effects?
How does Orexin Receptor Antagonist (ORA ) help you sleep?
New sleeping aids such as Suvorexant, Lebrexant, and Darilexant are orexin receptor antagonists ( ORA ) , and their mechanism of action is completely different from traditional sleeping pills .
📌 The unique mode of action of the new sleeping aid :
• Reduces wakefulness signals without forcing sedation - Unlike traditional sleeping pills, it does not suppress nerves, but allows the brain to fall asleep naturally.
• Maintains natural sleep structure - does not disrupt deep sleep and improves sleep repair function.
• It is non-addictive and can be used for a long time - long-term use will not produce tolerance, and no withdrawal symptoms will occur after stopping the drug ( Sun et al., 2021 ).
• Does not affect daytime mental state - no problems such as drowsiness and decreased concentration will occur the next day.
📌 Scientific research supports :
• Patients taking suvorexant experienced 43% fewer nighttime awakenings and more stable sleep ( Herring et al., 2016 ).
• Dauvilliers can increase the proportion of deep sleep without affecting daytime wakefulness ( Dauvilliers et al., 2022 ).
• Clinical trials of Lebrexant showed that there was no tolerance after 6 months of continuous use, and sleep remained stable after discontinuation of the drug ( Ueno et al., 2022 ).
4. Traditional sleeping pills vs. new generation sleeping pills (safety comparison)
|
Features |
Traditional sleeping pills (eg, diazepam, zopiclone) |
Newer sleep aids (such as suvorexant, lebrexant, darilexant) |
|
Mechanism of action |
Acts on GABA receptors to forcibly inhibit brain nerve activity |
Acts on orexin receptors to reduce wakefulness signals and allow the brain to fall asleep naturally |
|
Is it addictive? |
Long-term use can lead to addiction and increased tolerance |
No dependency, can be used for a long time |
|
Does it affect deep sleep? |
May reduce REM sleep and affect memory consolidation |
Does not affect deep sleep and improves sleep quality |
|
Morning state |
Morning drowsiness and decreased concentration |
Wake up in the morning without any effects |
These research data show that new sleeping aids such as Suvorexant are much safer than traditional sleeping pills, so more and more doctors recommend patients to choose these new drugs .
5. How to use sleeping pills scientifically to ensure the best sleep effect?
📌 Scientific medication recommendations :
💊 Recommended dose :
• Suvorexant ( 10-20mg ) - suitable for those who wake up easily at night and help maintain a full night's sleep .
• Lebrexan ( 5-10mg ) - suitable for difficulty falling asleep, helping the brain enter sleep mode faster .
• Dali Lexan ( 25mg ) - Suitable for shallow sleep, morning fatigue, and helps improve deep sleep .
💡 Note :
• Get at least 7 hours of sleep to avoid feeling tired the next day.
• Avoid using it with alcohol or caffeine to avoid affecting the efficacy of the drug.
• Adopt healthy sleep habits , such as reducing the use of electronic devices before bedtime and maintaining a regular sleep schedule , to improve overall sleep quality.
6. New generation of sleeping pills are a safer long-term option
Although traditional sleeping pills can help people fall asleep, long-term use can easily lead to addiction and may affect deep sleep and cognitive function . In contrast, new sleeping pills such as Suvorexant, Lebrexant, and Darilexant reduce wakefulness signals, allowing the brain to fall asleep naturally, are not addictive, and do not affect memory and daytime status , making them safer long-term sleeping aids .
If you want to choose a safer and more scientific way to help you sleep , these new sleeping pills may be your best choice.
🛒 Dayvigo lemborexant 2.5mg 100 tablets
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