Will I regain weight after stopping tepoxetine? How can I maintain my weight loss?
1. Telbutide: Why is it effective in helping with weight loss?
Tirzepatide is an innovative drug used to treat type 2 diabetes and assist in weight loss . It activates GLP-1 (glucagon-like peptide -1 ) and GIP (glucose-dependent insulinotropic polypeptide) receptors simultaneously to control blood sugar while reducing appetite, delaying gastric emptying and promoting fat metabolism .
📌 Why does tepol help with weight loss?
✅ Reduce appetite : By affecting the brain's satiety signals, people naturally eat less.
✅ Delay gastric emptying : Allow food to stay in the stomach longer, prolonging the feeling of fullness and reducing hunger.
✅ Improves insulin sensitivity : Helps the body regulate blood sugar more effectively and reduces fat accumulation.
✅ Promote fat metabolism : It not only reduces subcutaneous fat, but also reduces visceral fat, which has a positive effect on improving metabolic health.
Clinical research data: Weight loss effect of telopoietin
• The SURMOUNT-1 study ( Jastreboff et al., 2022 ) found that using a 15 mg dose of tebuconazole resulted in an average weight loss of 22.5% over 72 weeks , significantly exceeding other similar drugs.
• Compared with single GLP-1 agonists (such as semaglutide), tepote has a stronger weight loss effect , indicating that its unique dual mechanism brings better weight management effect.
However, many people gain weight back after stopping tepoxetine . Does this mean that the weight loss effect cannot be maintained in the long term? How can we avoid weight rebound?
2. Will weight rebound after stopping medication? Scientific data tells you the answer
Many patients taking telopoietin are concerned about whether they will gain weight back after stopping the drug, and if so, how much?
📌 Study data: Weight changes after discontinuation of tepoxetine
• The SURMOUNT-4 study ( Wilding et al., 2023 ) tracked patients’ weight changes after stopping tebuconazole. The results showed that:
• Within a year after stopping the drug, some patients regained about 6.9% of their weight , but it was still far below baseline levels.
• The amount of weight regained will vary depending on your lifestyle - if you continue to eat a healthy diet and exercise, you will regain less weight.
• Compared with people who have never used drugs, their weight after stopping the drug is still significantly lower than the initial baseline , indicating that the metabolic adjustments brought about by the drug have a lasting effect.
Why do I gain weight again after stopping medication?
❌ Appetite restoration - After discontinuation of tepoxetine, stimulation of GLP-1 and GIP receptors is reduced, leading to a gradual recovery of appetite.
❌ The basal metabolic rate may decrease - if a lot of muscle is lost during weight loss, the basal metabolic rate will decrease, and it will be easy to consume too many calories after stopping the medication.
❌ Failure to adjust eating and exercise habits - If you rely primarily on medication during weight loss without establishing long-term healthy habits, you are at greater risk of regaining weight after stopping the medication.
3. How to maintain weight loss results? Five strategies to help you maintain your weight
Although some weight may rebound after stopping the medication, through scientific methods, we can minimize weight rebound and maintain the weight loss effect for a long time .
✅ 1. Gradually reduce calorie intake to avoid excessive rebound
• Tipol helps reduce food intake, so you should not immediately resume your previous diet after stopping the medication . You can gradually increase your diet by 200-300 kcal / day to avoid a sharp rebound in weight.
• Choose high-protein, high-fiber foods, such as chicken breast, fish, beans, green leafy vegetables, and oats , to increase satiety and reduce the risk of overeating.
✅ 2. Maintain protein intake, protect muscles, and improve metabolism
• After stopping the medication, protein intake should still be maintained at 1.2-1.5g/kg of daily body weight to maintain muscle mass and prevent metabolic decline.
• For example, a person weighing 70kg should consume 84-105g of protein per day , which is equivalent to a piece of chicken breast + 2 eggs + 1 cup of yogurt + a portion of tofu.
✅ 3. Maintain exercise habits to prevent fat from returning
• Strength training ( 3-4 times a week) : strengthen muscles, improve basal metabolism, and reduce fat regain.
• Aerobic exercise ( 150-300 minutes per week) : such as brisk walking, running, swimming, and cycling, helps maintain cardiovascular health and stable weight.
• NEAT (non-exercise expenditure) : Increasing daily activities, such as walking more, standing while working, and doing housework , can help burn extra calories.
✅ 4. Continue to monitor your weight and adjust your lifestyle in a timely manner
• Measure your body weight once a week to avoid gaining weight without noticing.
• Pay attention to changes in waist circumference . If your waist circumference increases, it may mean that visceral fat is increasing and you need to adjust your diet and exercise.
• Use a health app or smartwatch to track your daily exercise and diet and maintain good living habits.
✅ 5. Maintain good sleep, reduce stress, and regulate hormones
• Lack of sleep increases the hunger hormone ghrelin and decreases leptin , making it easier for people to overeat ( Spiegel et al., 2004 ).
• Get 7-9 hours of quality sleep and avoid emotional eating caused by stress.
• Manage stress and reduce stress eating by using methods such as meditation, deep breathing, and yoga .
4. Conclusion: How to stabilize body weight after stopping tepoxetine?
📌 Conclusion: After stopping tepoxetine, weight regain depends on lifestyle modification
• Clinical studies have shown that after stopping medication, the body weight of some patients recovered by about 6.9% , but was still lower than the baseline level ( Wilding et al., 2023 ).
• The key to avoiding weight regain is to maintain a healthy lifestyle , including a proper diet, adequate protein, regular exercise, monitoring your weight and improving sleep .
If you plan to stop taking tepoxetine or hope to maintain your weight loss results for a long time, it is recommended that you establish healthy eating and exercise habits in advance and gradually adjust them after stopping the medication to avoid rapid weight gain . In this way, even without relying on medication, you can maintain a healthy weight and a good metabolic state for a long time.
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