Why can't you lose weight despite dieting and exercise? ——Exploring scientific solutions to stubborn obesity
1. Have you fallen into the weight loss misunderstanding of " diet + exercise " ?
Many people try to lose weight by eating less and exercising more. However, even with strict diet and daily exercise, weight loss may not be achieved or may even rebound. This may not be a problem of willpower, but a problem of the body's metabolic mechanism.
📌 Common weight loss bottlenecks:
✔ Weight stagnation after dieting: Long-term low calorie intake leads to a decrease in basal metabolism, and the body enters " energy saving mode " , making it difficult to continue losing weight even if you eat less.
✔ Exercise but no effect: Some people exercise a lot, but their body fat percentage remains almost unchanged. This may be due to insulin resistance and impaired fat metabolism, which makes it difficult to burn fat.
✔ It is easier to gain weight after repeated dieting: Repeated attempts at low-calorie diets lead to hormonal imbalances (such as leptin and insulin), and the body is more inclined to store fat.
💡 If your weight is stagnant or you tend to gain it back after losing weight, you may need to rethink your weight loss strategy!
2. Why is it so difficult to lose weight due to stubborn obesity? ——The difficulty of losing weight from the perspective of physiological mechanisms
Scientific research shows that obesity is not just a problem of excessive intake and lack of exercise, but involves multiple factors such as hormone regulation, insulin sensitivity, and metabolic adaptability.
📌 Key influencing factors:
🔹 Insulin resistance: High insulin levels inhibit fat burning and make the body more inclined to store fat, so even if calorie intake is reduced, the weight loss effect is limited.
🔹 Leptin imbalance: Leptin is a hormone that controls appetite. Obese people usually have higher leptin levels, but the body is insensitive to it, causing the brain to continuously send " hunger " signals and increase appetite.
🔹 Reduced basal metabolism: Long-term dieting or aging will reduce muscle mass, causing a decrease in basal metabolism, making it more difficult to lose weight.
📌 The traditional “ eat less, exercise more ” approach may not be effective for some people, especially those with stubborn obesity!
3. Mounjaro : How to break through stubborn obesity?
Traditional weight loss methods (such as dieting and exercise) are easily limited by hormonal regulation and metabolic adaptation. Tirzepatide ( Mounjaro ) uses the GLP-1 + GIP dual agonist mechanism to help the body break through the physiological weight loss bottleneck and solve the weight loss problem from the source.
📌 GLP-1 effect: reduce appetite, reduce glucagon secretion
✔ It acts on the appetite center of the brain, reduces hunger, and allows you to naturally reduce calorie intake.
✔ Delays gastric emptying, providing a longer-lasting feeling of fullness, and reducing overeating and mindless eating.
📌 GIP function: promote fat decomposition and improve energy metabolism
✔ Directly acts on fat cells, accelerates fat burning and improves metabolic efficiency.
✔ Improves insulin sensitivity, allowing the body to use energy more efficiently rather than storing it as fat.
📌 Clinical study data ( SURMOUNT-1 ):
• After 72 weeks, tebuconazole can reduce body weight by up to 22.5% , which is particularly effective for people who do not respond to traditional weight loss!
• More potent than Wegovy (semaglutide), which only achieved a maximum weight loss of 16.9% .
• More than 60% of users lost more than 20% of their body weight, far exceeding other weight loss programs.
💡 Compared with dieting and exercise, tipol can more scientifically regulate appetite, improve metabolism, and help patients with refractory obesity lose weight successfully.
4. How to lose weight scientifically and avoid rebound?
📌 If you have tried dieting and exercise and still have difficulty losing weight, you may need to start with hormone regulation and metabolic mechanisms.
📌 Mounjaro helps the body lose weight scientifically through the GLP-1 + GIP mechanism, making stubborn obesity controllable.
📌 Combined with a healthy diet and moderate exercise, long-term use of tirpotide can help maintain weight loss and reduce the risk of rebound.
💡 If you are facing a weight loss bottleneck, telopoietin may be your best breakthrough! 🚀
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