Will there be a rebound after stopping tipol? How to maintain weight loss results in the long term?
Telpotide is known as the strongest FDA -approved weight loss drug . In a 72- week clinical study, patients lost an average of 22.5% of their body weight , and 57% of them lost more than 20% . However, many users are worried: Will their weight rebound after stopping telpotide? How to maintain weight loss results in the long term?
This article will analyze the issue of weight management after stopping telportin and provide scientific methods, including diet adjustment, exercise strategy and lifestyle optimization , to help you maintain your ideal weight after stopping the medication and avoid rebound .
1. Will my weight rebound after I stop taking tepoxetine?
📌 The Nature of Weight Rebound: The Balance of Calories In vs. Calories Out The reason why tipol can help people lose weight is that it reduces appetite, delays gastric emptying, and increases fat burning through the dual agonist mechanism of GLP-1 + GIP , allowing people to actively consume fewer calories while burning more fat .
However, if good living habits are not developed after stopping the medication, the originally suppressed appetite may return, leading to increased calorie intake and thus weight gain.
📌 Clinical research data: weight changes after drug withdrawal
🔍 SURMOUNT-4 study (weight changes after discontinuation of tebuconazole) :
• After 72 weeks, all subjects had lost 20-22% of their body weight and were then randomly divided into a group that continued medication or a group that stopped medication .
• Those who continued to take the medication maintained their weight loss , while the group that stopped taking the medication regained an average of 14.5% of their body weight within a year .
• However, it is still about 10-12% lower than the starting weight , indicating that the long-term effect of tipol is still there.
📌 Key Findings
✔ After stopping the drug completely, appetite may partially return and weight may rebound , but usually not completely back to the original weight level.
✔ If you can maintain healthy eating and exercise habits after stopping the medication, your weight can be maintained for a long time and the rebound rate will be greatly reduced.
💡 Conclusion: Some people will experience weight rebound if they do not adjust their diet and exercise after stopping medication, but a correct lifestyle can effectively control the extent of rebound and maintain long-term weight loss effects.
2. How to maintain weight loss results in the long term and avoid rebound?
📌 The keys to maintaining your weight are:
• Establish a long-term sustainable diet and avoid returning to a high-calorie diet.
• Adhere to a scientific exercise plan to improve basal metabolism and prevent fat from re-accumulating.
• Manage appetite and psychological factors to avoid weight regain due to emotional eating.
2.1. Dietary adjustment: How to eat healthily and prevent appetite rebound?
📌 Goals of dietary control :
✔ Prevent excessive calorie intake and avoid overeating .
✔ Ensure protein intake to prevent muscle loss and improve basal metabolism .
✔ Reduce the intake of refined carbohydrates, stabilize blood sugar, and reduce hunger .
Best Diet Strategies
✔ High-protein diet ( 25-30% of total calories):
• Why? High protein can increase satiety, maintain muscle mass, and improve basal metabolism .
• Recommended foods : chicken breast, fish, shrimp, eggs, Greek yogurt, beans, etc.
✔ Low in refined carbohydrates (to avoid drastic fluctuations in blood sugar) :
• Why? Refined carbohydrates (like white rice and white bread) cause insulin spikes, leading to greater hunger .
• Recommended alternatives : low GI carbohydrates such as brown rice, whole wheat bread, quinoa, sweet potatoes, etc.
✔ Healthy fats (help maintain hormone balance) :
• Recommended foods : avocado, olive oil, nuts, and deep-sea fish.
💡 Conclusion: Continuing to maintain a high-protein, low-refined carbohydrate diet after stopping medication can effectively reduce appetite rebound and reduce the possibility of weight regain.
2.2. Exercise plan: How to maintain weight through exercise?
📌 Three major effects of exercise
✔ Prevent a decrease in basal metabolism : Muscle loss will reduce metabolism, while exercise can maintain muscle mass and maintain higher energy expenditure .
✔ Helps burn fat : Combining aerobic exercise and strength training can improve the body's ability to burn fat.
✔ Improve insulin sensitivity : reduce blood sugar fluctuations, reduce appetite, and prevent the risk of diabetes.
📌 Best Movement Strategy
1️Aerobic exercise ( 3-5 days a week)
✔ Recommended exercise : brisk walking, jogging, cycling, swimming, 30-45 minutes each time.
✔ Function : Improve cardiopulmonary endurance and help burn fat continuously.
2️Resistance training ( 2-3 times per week)
✔ Recommended training : squats, deadlifts, dumbbell training, core training.
✔ Effect : Increase muscle mass, improve basal metabolism, and reduce weight regain.
💡 Conclusion: Exercising 3-5 days a week after stopping medication can effectively reduce fat accumulation and improve weight loss maintenance rate.
2.3. How to adjust your mental state and avoid emotional eating?
📌 Psychological problems that may occur after drug withdrawal
• “ I can go back to eating normally ” → Ends up overeating and gaining weight back.
• “ I get anxious when I gain a little weight ” → Over-dieting leads to a more severe rebound in appetite.
📌 Coping strategies
✔ Set long-term goals, not short-term weight numbers (focus on body composition and health indicators).
✔ Record your daily diet and exercise to establish good habits .
✔ Find alternative ways to cope with stress (yoga, meditation, not overeating).
💡 Conclusion: Psychological management is an important part of long-term weight maintenance, establishing sustainable eating and exercise habits rather than relying on short-term extreme methods.
3. Conclusion: How to maintain long-term weight loss after stopping medication?
📌 After stopping tepoxetine, some people may experience a certain degree of weight rebound if they do not adjust their lifestyle, but the following strategies can effectively prevent this:
✔ Maintain a high-protein, low-refined carbohydrate diet to reduce appetite rebound .
✔ Stick to aerobic + resistance training 3-5 days a week to improve metabolism and prevent weight gain .
✔ Manage your expectations and avoid excessive dieting or overeating due to anxiety .
💡 Final conclusion: The weight loss effect of tebuconazole can be maintained for a long time, but the key is to develop good eating and exercise habits, establish a sustainable health management strategy, and avoid dependence on drugs.
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