Zithromac Pfizer Original Azithromycin Tablets 250mg 60 Tablets

1. Basic information of the drug

• Generic Name : Azithromycin

• Trade Name : Zithromac

• Specification : 250mg/tablet, 60 tablets/box

• Manufacturer : Pfizer

• Drug category : Macrolide antibiotics

2. Indications

Zithromac is indicated for the treatment of a variety of infections caused by susceptible bacteria, including:

1. Respiratory tract infections

   • Acute pharyngitis and tonsillitis (caused by Streptococcus pyogenes).

   • Pneumonia, bronchitis (caused by Streptococcus pneumoniae, Haemophilus influenzae, or Mycoplasma pneumoniae).

   • Acute otitis media, sinusitis.

2. Skin and soft tissue infections

   • Infections caused by Staphylococcus aureus, Streptococcus pyogenes, etc.

3. Sexually transmitted diseases

   • Urethritis and cervicitis caused by Chlamydia trachomatis or non-multidrug-resistant gonococci.

   • Chancroid caused by Haemophilus ducreyi (male).

4. Other infections

   • Pelvic inflammatory disease (needs to be combined with anti-anaerobic drugs).

3. Usage and Dosage

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  • Routine infections : total dose 1500 mg, 500 mg (2 tablets) on the first day, then 250 mg (1 tablet) daily for the next 4 days.

  • Sexually transmitted diseases : 1000 mg (4 tablets) taken orally as a single dose.

• child

  • The dose is calculated based on body weight, and the total dose should not exceed 1500 mg. For example, for otitis media or pneumonia: 10 mg/kg on the first day, and 5 mg/kg on the next 4 days.

4. Adverse Reactions

1. Common reactions

   • Gastrointestinal: diarrhea, nausea, abdominal pain, vomiting.

2. Severe reactions (rare but worth watching out for)

   • Allergic reactions: rash, angioedema, anaphylactic shock.

   • Hepatotoxicity: cholestatic jaundice, liver failure.

   • Cardiac toxicity: QT interval prolongation, arrhythmias.

5. Taboos and precautions

1. Taboo group

   • Allergic to macrolide drugs.

   • Patients with a history of cholestatic jaundice or severe liver dysfunction.

2. Precautions

   • Hepatic impairment : Mild to moderate patients need to monitor liver function; severe liver disease is contraindicated.

   • Cardiac Risks : Avoid use in patients with QT prolongation or cardiac arrhythmias.

   • Drug Interactions :

     • The combined use of ergot derivatives and pimozide is prohibited.

     • Use with caution with warfarin, digoxin, or statins.

VI. Use in Special Populations

• Pregnant women : Use only if the benefits outweigh the risks.

• Lactation : It is recommended to suspend breastfeeding during medication.

• Children : The efficacy and safety for some indications (such as pharyngitis in children under 2 years old) have not been fully clarified.

VII. Storage conditions

• Keep in sealed container away from light, the temperature should not exceed 30℃.

• Please keep medicines out of reach of children.

8. Conclusion

Zithromac is an azithromycin tablet originally developed by Pfizer. It has broad-spectrum antibacterial activity and is suitable for infections caused by a variety of sensitive bacteria. It is easy to use (once a day) and has a short course of treatment, but attention should be paid to liver function and cardiac toxicity risks. When using it, you should strictly follow the doctor's instructions to avoid abuse leading to drug resistance.